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    2015-5-1 · Introduction. The hepatitis B virus (HBV), which leads to chronic hepatitis B (CHB), encodes several different viral proteins, including DNA polymerase, surface antigen (HBsAg), core antigen, and the X protein (HBx) .The mechanisms for establishing and maintaining chronic infections are still unknown; however, evidence suggests that HBV has developed strategies …The Pro-Inflammatory Cytokine Cascade | SpringerLinkThe production of pro-inflammatory cytokines is a prerequisite for initiating the anti-infectious process, whereas their exacerbated production during severe inflammation may contribute to deleterious consequences. The capacity of interleukin (IL)-l and tumor necrosis factor-alpha (TNF-a) to induce inflammatory mediators contributes to their ...

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